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What does the oil do? CBD y
how should I use it?

CBD oil can be applied to the skin, so that it acts directly on the affected area: it can be on muscles, muscles, muscles and joints. inflamed , areas irritated, eczema, psoriasis, acne.

Benefits of CBD and CBD Oil

Cannabis (yes, Hemp is Cannabis) is a medicinal plant that has been cultivated and used for over 5,000 years.
At Bovē Health we take advantage of the advances in the biotechnology and the science to offer the properties of CBD (Cannabidiol), Cannabis and many other plants, to enhance the activity of a wide variety of processes in our body, our mind and our body. skin and our minds.
CBD or CBD Oil has been widely demonstrated in several scientific studies to potentially improve the quality of life in people with social anxiety, insomnia, chronic pain and has even been shown to have incredible dermo-cosmetic properties.
CBD Oil is a Cannabis oil, which is mixed with the extract of Cannabis Sativa (Hemp), CBD or Cannabidiol, which in many countries is recommended for internal use to treat pain or anxiety, although in Spain it is only regulated for cosmetic use and is the only use we can recommend to our clients and friends.
The use of CBD has been shown to reduce pain and inflammation, reduce anxiety and stimulate appetite in the same way that marijuana does, but without affecting your mental state, and CBD reduces the psychoactive effects of THC. This compound from the Cannabis plant has also been shown to help treat some types of seizures in people with epilepsy.
Endocannabinoid System

What is CBD oil used for?

Unlike THC, CBD does not have a strong connection to cannabinoid receptors in the brain. These are the molecules that THC binds to in order to create psychoactive effects.
In contrast, CBD influences other receptors, such as the opioid receptors that control pain. It also affects glycine receptors. These control serotonin, a brain chemical known as the 'feel good' hormone.
To date it has been documented that CBD or CBD Oil can treat a variety of problems and pains, including:
01-Bove-Anxiety

CBD Oil for Anxiety

A review of studies published in 2015 in the journal Neurotherapeutics suggests that CBD could help treat anxiety disorders.
The study authors report that CBD had potent anxiety-relieving effects in animal research. But the results were not as expected.
In most studies, lower doses of CBD (10 milligrams per kilogram, mg/kg, or less) improved some anxiety symptoms, but higher doses (100 mg/kg or more) had almost no effect. The way CBD acts in the brain may explain why this happens. At low doses, CBD can act just like the surrounding molecules that normally bind to the receptor, which 'boosts' its signalling.
However, at higher doses, excessive activity at the receptor site can cause the opposite effect. This would remove the useful effects of CBD. There are not many trials of studies looking at the anxiety-relieving effects of CBD in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry.
For the study57 men took CBD oil or a placebo (sugar pill) before a public speaking event. The researchers based anxiety levels on measures such as blood pressure and heart rate. They also used a fairly reliable test of mood called the Visual Analogue Mood Scale (VAMS).
Men who took 300 mg of CBD oil showed less anxiety than those who received a placebo. Interestingly, men who took 100 mg or 600 mg of CBD oil did not have these results.
Dream-bove-bottom1

CBD oil for better sleep.

CBD oil could help people with substance use disorder, says study 2015 review published in the journal Substance Abuse.
The review looked at 14 published studies. Nine of the studies looked at effects in animals, and five studies looked at effects in humans. The researchers reported that CBD showed promise in treating people with sleep disorders, reducing the time it takes to fall asleep by more than 40%, and decreasing the % of sleep disturbances, promising a restful sleep.
For example, CBD without THC did not help reduce withdrawal symptoms from opioid use. In contrast, it did reduce drug-seeking behaviour in users of cocaine, methamphetamine and similar drugs.
Some experts suggest that CBD may help treat cannabis and nicotine dependence, but more research is needed.
Bove-Ibuprofen_v1

CBD for Chronic Pain

Doctors may prescribe medical marijuana to people with treatment-resistant pain, such as those with terminal cancer. There is some evidence that CBD plays a role in this benefit.
A research interesting is a 2012 study published in the Journal of Experimental Medicine. Researchers injected rats with chemicals that trigger inflammation. Then they gave them CBD. The rats given CBD experienced less inflammation and nerve pain (pain caused by nerve damage). Scientists believe that CBD reduces nerve pain by binding to receptors in the brain that control the speed at which nerve signals pass between nerve cells.
Psoriasis and CBD

Does CBD oil work to relieve psoriasis?

Psoriasis is a chronic disease, mediated by our own immune system, which includes psoriasis and psoriatic arthritis. It is the result of abnormal immune activity that promotes inflammation, which can affect the skin or joints. Visibly, it is characterised in part by plaques and scales on the skin resulting from an overactive immune system and rapid reproduction of skin cells. But because it is a systemic disease, there may be inflammation under the skin. This inflammation affects the joints and can cause swelling, stiffness and joint pain.
CBD, and also CBD Oil, has the ability to bind to receptors in the body that are part of the human cannabinoid system, called endocannabinoids, which can influence pain, itch and inflammatory mechanisms," say many dermatologists and scientists. "We know that when CBD binds to CB2 [cannabinoid receptor type 2], as well as other receptors, it can participate not only in anti-inflammatory activity, but can facilitate a number of activities that resolve inflammation. It may stimulate the secretion and recruitment of cells that are important for clearing waste and allowing proper skin maturation and healing.
Results from a 2019 study investigating a topical CBD ointment applied to skin lesions twice daily for two months indicated that CBD ointment improved skin hydration and elasticity, as well as quality of life measures assessed by the Psoriasis Area Severity Index.
A more recent study published in late 2020 examined a CBD-containing shampoo that was effective in reducing the severity of scalp inflammation, itching and burning in patients with psoriasis or seborrhoeic dermatitis.
1_Bove-Epilepsy

Cannabis as a treatment for epilepsy

Epidiolex is used to treat two rare forms of epilepsy in children under 2 years of age: Dravet syndrome and Lennox-Gastaut syndrome. These are very rare genetic disorders that cause lifelong seizures beginning in the first year of life. Outside of these two disorders, the efficacy of CBD in the treatment of seizures is uncertain. Even with Epidiolex, it is unclear whether the anticonvulsant effects come from CBD or some other factor.

Sources

Palmieri B, Laurino B, Vadalà M. A therapeutic effect of CBD-enriched ointment in inflammatory skin diseases and cutaneous scars. Clin Ter. 2019;(2):93-99.

Vincenzi C, Tosti A. Efficacy and tolerability of a shampoo containing broad-spectrum cannabidiol in the treatment of scalp inflammation in patients with mild to moderate scalp psoriasis or seborrheic dermatitis. Skin Appendage Disord. 2020;6(6):355-361.

Cather J. CBD in the holistic practice of dermatology. Pract Dermatol. July 2020;41-42,56.

Epidiolex (cannabidiol). Carlsbad, CA: Genentech Biosciences. Revised Apr 2020. https://www.epidiolex.com/sites/default/files/pdfs/1120/EPX-03645-1120_EPIDIOLEX_(cannabidiol)_USPI.pdf.

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