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What does the CBD y
how should I use it?

CBD and CBG are some of the most versatile natural substances in the world. They can be applied directly to the skin, so that they act directly on the affected area: this can be on inflamed muscles, irritated areas, eczema, psoriasis, acne.

Benefits and properties of CBD

Cannabis is a medicinal plant that has been cultivated and used for more than 5,000 years.
At Bovē Health we take advantage of advances in biotechnology and science to offer the properties of CBD (Cannabidiol) and Cannabis to improve the activity of a wide variety of processes in our body.

What is CBD oil?

This cannabis extract can help treat nerve pain, anxiety and epilepsy.
CBD oil is an extract of Cannabis sativa (Hemp), the same plant used to make marijuana, only without THC.
CBD oil can treat pain, lower anxiety and stimulate appetite in the same way that marijuana does, but without affecting your mental state. CBD may also help treat some types of seizures.
CBD is short for cannabidiol, one of the two chemicals in cannabis with the most health benefits. The other chemical is tetrahydrocannabinol (THC).
THC is responsible for the psychoactive effects of cannabis, i.e. what makes you feel "high". CBD oil is generally THC-free, although there may be traces in products sold in certain states.
CBD oil contains CBD mixed with a base (carrier) oil, such as coconut oil or hemp seed oil. Bottled CBD oil is called tincture and is sold in different concentrations.

What is CBD oil used for?

Unlike THC, CBD does not have a strong connection to cannabinoid receptors in the brain. These are the molecules that THC binds to in order to create psychoactive effects.
In contrast, CBD influences other receptors, such as the opioid receptors that control pain. It also affects glycine receptors. These control serotonin, a brain chemical known as the 'feel good' hormone.
Supporters of CBD use claim that CBD oil can treat a variety of health problems, including:

Anxiety

A review of studies published in 2015 in the journal Neurotherapeutics suggests that CBD could help treat anxiety disorders.
The study authors report that CBD had potent anxiety-relieving effects in animal research. But the results were not as expected.
In most studies, lower doses of CBD (10 milligrams per kilogram, mg/kg, or less) improved some anxiety symptoms, but higher doses (100 mg/kg or more) had almost no effect. The way CBD acts in the brain may explain why this happens. At low doses, CBD can act just like the surrounding molecules that normally bind to the receptor, which 'boosts' its signalling.
However, at higher doses, excessive activity at the receptor site can cause the opposite effect. This would remove the useful effects of CBD. There are not many trials of studies looking at the anxiety-relieving effects of CBD in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry.
For the study57 men took CBD oil or a placebo (sugar pill) before a public speaking event. The researchers based anxiety levels on measures such as blood pressure and heart rate. They also used a fairly reliable test of mood called the Visual Analogue Mood Scale (VAMS).
Men who took 300 mg of CBD oil showed less anxiety than those who received a placebo. Interestingly, men who took 100 mg or 600 mg of CBD oil did not have these results.

Addiction

CBD oil could help people with substance use disorder, says study 2015 review published in the journal Substance Abuse.
The review looked at 14 published studies. Nine of the studies looked at effects in animals, and five studies looked at effects in humans. The researchers reported that CBD showed promise in treating people with addictions to opioids, cocaine or psychostimulants. However, CBD affected each type of addiction very differently.
For example, CBD without THC did not help reduce withdrawal symptoms from opioid use. In contrast, it did reduce drug-seeking behaviour in users of cocaine, methamphetamine and similar drugs.
Some experts suggest that CBD may help treat cannabis and nicotine dependence, but more research is needed.

Pain

Doctors may prescribe medical marijuana to people with treatment-resistant pain, such as those with terminal cancer. There is some evidence that CBD plays a role in this benefit.
A research interesting is a 2012 study published in the Journal of Experimental Medicine. Researchers injected rats with chemicals that trigger inflammation. Then they gave them CBD. The rats given CBD experienced less inflammation and nerve pain (pain caused by nerve damage). Scientists believe that CBD reduces nerve pain by binding to receptors in the brain that control the speed at which nerve signals pass between nerve cells.
However, there are not many studies examining the use of CBD to treat chronic pain in people. The studies that do exist almost always involve THC. This makes it difficult to isolate the unique effects of CBD.

High blood pressure

CBD oil may reduce the risk of heart disease by relieving high blood pressure in some people, according to a new study. a study of 2017 published in JCI Insight
For the study, nine healthy men took 600 mg of CBD or the same dose of a placebo. The men who took CBD had lower blood pressure before and after stressful things, such as exercise or extreme cold.
The study also looked at stroke volume (the amount of blood left in the heart after a heartbeat). The stroke volume in the men taking CBD was lower than in the placebo group, meaning the heart was pumping more efficiently.
The study suggests that CBD oil may be a good complementary therapy for people whose high blood pressure is affected by stress and anxiety.
However, there is no evidence that CBD oil alone can treat high blood pressure or prevent it in people at risk. Although stress can complicate high blood pressure, it cannot cause it.

Seizures

In June 2018, the US Food and Drug Administration (FDA) approved Epidiolex, an oral CBD solution.
Epidiolex is used to treat two rare forms of epilepsy in children under 2 years of age: Dravet syndrome and Lennox-Gastaut syndrome. These are very rare genetic disorders that cause lifelong seizures beginning in the first year of life. Outside of these two disorders, the efficacy of CBD in the treatment of seizures is uncertain. Even with Epidiolex, it is unclear whether the anticonvulsant effects come from CBD or some other factor.
There is some tests that CBD interacts with anticonvulsant drugs such as Onfi (clobazam) and increases their concentration in the blood. However, more research is needed.
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